{"id":6424,"date":"2022-12-19T09:34:00","date_gmt":"2022-12-19T08:34:00","guid":{"rendered":"https:\/\/botanico.uclm.es\/en\/project\/thymoquinone-loaded-chitosan-nanoparticles-as-natural-preservative-agent-in-cosmetic-products\/"},"modified":"2022-12-21T15:23:07","modified_gmt":"2022-12-21T14:23:07","slug":"thymoquinone-loaded-chitosan-nanoparticles-as-natural-preservative-agent-in-cosmetic-products","status":"publish","type":"project","link":"https:\/\/botanico.uclm.es\/en\/project\/thymoquinone-loaded-chitosan-nanoparticles-as-natural-preservative-agent-in-cosmetic-products\/","title":{"rendered":"Thymoquinone-Loaded Chitosan Nanoparticles as Natural Preservative Agent in Cosmetic Products"},"content":{"rendered":"<style type=\"text\/css\"> \n#cmsms_row_69f898c9b2e7a .cmsms_row_outer_parent { \n\tpadding-top: 0px; \n} \n\n#cmsms_row_69f898c9b2e7a .cmsms_row_outer_parent { \n\tpadding-bottom: 50px; \n} \n\n<\/style><div id=\"cmsms_row_69f898c9b2e7a\" class=\"cmsms_row cmsms_color_scheme_default\">\n<div class=\"cmsms_row_outer_parent\">\n<div class=\"cmsms_row_outer\">\n<div class=\"cmsms_row_inner\">\n<div class=\"cmsms_row_margin\">\n<div class=\"cmsms_column one_first\">\n<div class=\"cmsms_text\">\n<h2 class=\"Heading\">Resumen<\/h2>\n<p>The current status of controversy regarding the use of certain preservatives in cosmetic products makes it necessary to seek new ecological alternatives that are free of adverse effects on users. In our study, the natural terpene thymoquinone was encapsulated in chitosan nanoparticles. The nanoparticles were characterized by DLS and TEM, showing a particle size of 20 nm. The chemical structure, thermal properties, and release profile of thymoquinone were evaluated and showed a successful stabilization and sustained release of terpenes. The antimicrobial properties of the nanoparticles were evaluated against typical microbial contaminants found in cosmetic products, showing high antimicrobial properties. Furthermore, natural moisturizing cream inoculated with the aforementioned microorganisms was formulated with thymoquinone-chitosan nanoparticles to evaluate the preservative efficiency, indicating its promising use as a preservative in cosmetics. \u00a9 2022 by the authors. Licensee MDPI, Basel, Switzerland.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":[],"pj-categs":[74],"pj-tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Thymoquinone-Loaded Chitosan Nanoparticles as Natural Preservative Agent in Cosmetic Products - Instituto Bot\u00e1nico<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/botanico.uclm.es\/en\/project\/thymoquinone-loaded-chitosan-nanoparticles-as-natural-preservative-agent-in-cosmetic-products\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Thymoquinone-Loaded Chitosan Nanoparticles as Natural Preservative Agent in Cosmetic Products - Instituto Bot\u00e1nico\" \/>\n<meta property=\"og:url\" content=\"https:\/\/botanico.uclm.es\/en\/project\/thymoquinone-loaded-chitosan-nanoparticles-as-natural-preservative-agent-in-cosmetic-products\/\" \/>\n<meta property=\"og:site_name\" content=\"Instituto Bot\u00e1nico\" \/>\n<meta property=\"article:modified_time\" content=\"2022-12-21T14:23:07+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/botanico.uclm.es\/en\/project\/thymoquinone-loaded-chitosan-nanoparticles-as-natural-preservative-agent-in-cosmetic-products\/\",\"url\":\"https:\/\/botanico.uclm.es\/en\/project\/thymoquinone-loaded-chitosan-nanoparticles-as-natural-preservative-agent-in-cosmetic-products\/\",\"name\":\"Thymoquinone-Loaded Chitosan Nanoparticles as Natural Preservative Agent in Cosmetic Products - 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