{"id":6495,"date":"2021-12-19T09:56:37","date_gmt":"2021-12-19T08:56:37","guid":{"rendered":"https:\/\/botanico.uclm.es\/en\/project\/polyester-polymeric-nanoparticles-as-platforms-in-the-development-of-novel-nanomedicines-for-cancer-treatment\/"},"modified":"2022-12-21T17:20:20","modified_gmt":"2022-12-21T16:20:20","slug":"polyester-polymeric-nanoparticles-as-platforms-in-the-development-of-novel-nanomedicines-for-cancer-treatment","status":"publish","type":"project","link":"https:\/\/botanico.uclm.es\/en\/project\/polyester-polymeric-nanoparticles-as-platforms-in-the-development-of-novel-nanomedicines-for-cancer-treatment\/","title":{"rendered":"Polyester polymeric nanoparticles as platforms in the development of novel nanomedicines for cancer treatment"},"content":{"rendered":"<style type=\"text\/css\"> \n#cmsms_row_69e22aa5dd602 .cmsms_row_outer_parent { \n\tpadding-top: 0px; \n} \n\n#cmsms_row_69e22aa5dd602 .cmsms_row_outer_parent { \n\tpadding-bottom: 50px; \n} \n\n<\/style><div id=\"cmsms_row_69e22aa5dd602\" class=\"cmsms_row cmsms_color_scheme_default\">\n<div class=\"cmsms_row_outer_parent\">\n<div class=\"cmsms_row_outer\">\n<div class=\"cmsms_row_inner\">\n<div class=\"cmsms_row_margin\">\n<div class=\"cmsms_column one_first\">\n<div class=\"cmsms_text\">\n<h2 class=\"Heading\">Resumen<\/h2>\n<p>Many therapeutic agents have failed in their clinical development, due to the toxic effects associated with non-transformed tissues. In this context, nanotechnology has been exploited to overcome such limitations, and also improve navigation across biological barriers. Amongst the many materials used in nanomedicine, with promising properties as therapeutic carriers, the following one stands out: biodegradable and biocompatible polymers. Polymeric nanoparticles are ideal candidates for drug delivery, given the versatility of raw materials and their feasibility in large-scale production. Furthermore, polymeric nanoparticles show great potential for easy surface modifications to optimize pharmacokinetics, including the half-life in circulation and targeted tissue delivery. Herein, we provide an overview of the current applications of polymeric nanoparticles as platforms in the development of novel nanomedicines for cancer treatment. In particular, we will focus on the raw materials that are widely used for polymeric nanoparticle generation, current methods for formulation, mechanism of action, and clinical investigations. \u00a9 2021 by the authors. Licensee MDPI, Basel, Switzerland.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":[],"pj-categs":[74],"pj-tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Polyester polymeric nanoparticles as platforms in the development of novel nanomedicines for cancer treatment - Instituto Bot\u00e1nico<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/botanico.uclm.es\/en\/project\/polyester-polymeric-nanoparticles-as-platforms-in-the-development-of-novel-nanomedicines-for-cancer-treatment\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Polyester polymeric nanoparticles as platforms in the development of novel nanomedicines for cancer treatment - Instituto Bot\u00e1nico\" \/>\n<meta property=\"og:url\" content=\"https:\/\/botanico.uclm.es\/en\/project\/polyester-polymeric-nanoparticles-as-platforms-in-the-development-of-novel-nanomedicines-for-cancer-treatment\/\" \/>\n<meta property=\"og:site_name\" content=\"Instituto Bot\u00e1nico\" \/>\n<meta property=\"article:modified_time\" content=\"2022-12-21T16:20:20+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/botanico.uclm.es\/en\/project\/polyester-polymeric-nanoparticles-as-platforms-in-the-development-of-novel-nanomedicines-for-cancer-treatment\/\",\"url\":\"https:\/\/botanico.uclm.es\/en\/project\/polyester-polymeric-nanoparticles-as-platforms-in-the-development-of-novel-nanomedicines-for-cancer-treatment\/\",\"name\":\"Polyester polymeric nanoparticles as platforms in the development of novel nanomedicines for cancer treatment - 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